Progressive Retinal Atrophy (Persian) is retinal atrophy in cats caused due to mutation in the Aryl-hydrocarbon interacting protein-Like 1 (AIPL1) gene resulting in a stop codon. This mutation is found mainly in Persian cats. Persian progressive retinal atrophy is characterized by progressive blindness. Cats with one normal and one mutated gene (carriers) have Retinal Pigment Epithelium changes but maintain normal vision without photoreceptor loss. Mating between two carrier cats is expected to produce 25% blind kittens.
Method
Sanger Sequencing
Sample Type
EDTA Blood (>=3mL)
Transport Condition
The sample should be transported at 4°C. (Refer to MBG-C0014)
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 5 working days.
Samples delivered after 11:00 AM will be processed the next working day (unless urgent).
Urgent Samples will be reported within 72 hours and will be charged double.
Progressive Retinal Atrophy (Persian) is retinal atrophy in cats caused due to mutation in the Aryl-hydrocarbon interacting protein-Like 1 (AIPL1) gene resulting in a stop codon. This mutation is found mainly in Persian cats. Persian progressive retinal atrophy is characterized by progressive blindness. Cats with one normal and one mutated gene (carriers) have Retinal Pigment Epithelium changes but maintain normal vision without photoreceptor loss. Mating between two carrier cats is expected to produce 25% blind kittens.
Method
Sanger Sequencing
Sample Type
EDTA Blood (>=3mL)
Transport Condition
The sample should be transported at 4°C. (Refer to MBG-C0014)
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 5 working days.
Samples delivered after 11:00 AM will be processed the next working day (unless urgent).
Urgent Samples will be reported within 72 hours and will be charged double.
