DNA-protein kinase catalytic subunit (DNA-PKcs) gene in equine. This mutation causes a frame-shift mutation and premature termination and results in an inactive DNA-PKcs protein. Severe combined immunodeficiency (SCID) equine foals are normal at birth but soon after present signs such as elevated temperature, respiratory stress, and diarrhea, typically between 2-8 weeks of age. Affected foals do not survive past the first six months of life. Both male and female foals are equally affected.
Method
Sanger Sequencing
Sample Type
EDTA Blood (>=3mL)
Transport Condition
The sample should be transported at 4°C. (Refer to MBG-C0014)
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 5 working days.
Samples delivered after 11:00 AM will be processed the next working day (unless urgent).
Urgent Samples will be reported within 72 hours and will be charged double.
DNA-protein kinase catalytic subunit (DNA-PKcs) gene in equine. This mutation causes a frame-shift mutation and premature termination and results in an inactive DNA-PKcs protein. Severe combined immunodeficiency (SCID) equine foals are normal at birth but soon after present signs such as elevated temperature, respiratory stress, and diarrhea, typically between 2-8 weeks of age. Affected foals do not survive past the first six months of life. Both male and female foals are equally affected.
Method
Sanger Sequencing
Sample Type
EDTA Blood (>=3mL)
Transport Condition
The sample should be transported at 4°C. (Refer to MBG-C0014)
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 5 working days.
Samples delivered after 11:00 AM will be processed the next working day (unless urgent).
Urgent Samples will be reported within 72 hours and will be charged double.
