Hyperkalemic Periodic Paralysis (HYPP) is caused by a missense mutation in the SCN4A gene that produces an altered alpha chain of the skeletal muscle sodium channel in horses. Specifically, the change in the DNA causes a substitution from phenylalanine to leucine of the protein product (sodium channel).
Method
Sanger Sequencing
Sample Type
EDTA Blood (>=3mL)
Transport Condition
The sample should be transported at 4°C. (Refer to MBG-C0014)
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 5 working days.
Samples delivered after 11:00 AM will be processed the next working day (unless urgent).
Urgent Samples will be reported within 72 hours and will be charged double.
Hyperkalemic Periodic Paralysis (HYPP) is caused by a missense mutation in the SCN4A gene that produces an altered alpha chain of the skeletal muscle sodium channel in horses. Specifically, the change in the DNA causes a substitution from phenylalanine to leucine of the protein product (sodium channel).
Method
Sanger Sequencing
Sample Type
EDTA Blood (>=3mL)
Transport Condition
The sample should be transported at 4°C. (Refer to MBG-C0014)
Turn Around Time (TAT)
The Turnaround (TAT) for routine samples is within 5 working days.
Samples delivered after 11:00 AM will be processed the next working day (unless urgent).
Urgent Samples will be reported within 72 hours and will be charged double.
