Molecular Biology & Genetics Laboratory

Species Specific Services


Services grouped by species of interest.


Avian Camelid Equine Feline Canine


Validated    
Assay Code See Below
Description Mycobacterium is a genus of Actinobacteria, family Mycobacteriaceae. Over 190 species are recognized in this genus. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (Mycobacterium tuberculosis) and leprosy (Mycobacterium leprae) in humans. Bovine tuberculosis is a chronic disease of animals and humans caused by Mycobacterium bovis. In a large number of countries it is a major infectious disease among cattle, other domesticated animals, and certain wildlife species. Other members of the Mycobacterium genus include M. caprae (considered to be a primary pathogen of goats) and M. pinnipedii, a pathogen of fur seals and sea lions. Aerosol exposure to M. bovis is considered to be the most frequent route of infection of cattle, but infection by ingestion of contaminated material also occurs. After infection, nonvascular nodular granulomas known as tubercles may develop. Characteristic tuberculous lesions occur most frequently in the lungs and the retropharyngeal, bronchial and mediastinal lymph nodes as well as liver, spleen and other organs. Clinical signs include weakness, anorexia, emaciation, dyspnoea, enlargement of lymph nodes, and cough, particularly with advanced tuberculosis.

Mycobacterium avium subspecies paratuberculosis (MAP) is an obligate pathogenic bacterium and the causative agent of Johne's disease, which affects ruminants such as cattle, and also causes Crohn's disease in humans.

Avian tuberculosis, or avian mycobacteriosis, is an important disease that affects companion, captive exotic, wild and domestic birds and mammals and is most often caused by Mycobacterium avium subsp. avium (M. a. avium).The disease is characterized by chronic and progressive wasting, weakness and diarrhoea. The primary lesions of avian tuberculosis in birds are nearly always in the intestinal tract. Diagnosis of avian tuberculosis in birds depends on the demonstration of M. avium avium) in excretions or secretions of live birds or liver and spleen of dead birds.

Pathogens Tested
  • APM-037 : Mycobacterium avium subspecies avium (This assay includes the detection of Mycobacterium species and Mycobacterium avium subspecies avium.)
  • APM-038 : Mycobacterium Species (This assay includes the detection of Mycobacterium species only. This Assay can detect M. austroafricanum, M.avium subsp. avium,M.bovis BCG, M.chelonae,M.gordonae, M.fortuitum subsp.fortuitum, M.insubricum, M.intracellulare, M.kansasii, M.marium, M.mucogenicum, M.peregrinum, M.porcinum, M.scrofulaceum, M.setense, M.simiae, M.smegmatis, M.terrae, M.tuberculosis, M.ulcerans, M.xenopi)
  • APM-039 : Mycobacterium avium subspecies paratuberculosis (This assay includes the detection of Mycobacterium species and Mycobacterium avium subspecies paratuberculosis.)
  • APM-100: Mycobacterium tuberculosis (This assay includes the detection of Mycobacterium species and Mycobacterium tuberculosis.)

Method Real- Time PCR.
Sample Type
Tissue (Intestinal tract, liver, spleen), Stool, Culture, Swab/Secretion (Respiratory), EDTA Blood, Milk, CSF, Gastric Lavage, Tissue on FTA Card.
Transport Condition Samples should be transported at 4°C. Stool and milk must be frozen after collection.
Turn Around Time (TAT) Normal Turnaround time for pathogen Identification is within 5 working days.
Urgent Samples will be reported within half of the minimum test period & will be Charged Double.
Samples delivered after 11:00 AM will be processed next working day unless urgent.

Links




Molecular Biology & Genetics Laboratory

Species Specific Services


Services grouped by species of interest.


Avian Camelid Equine Feline Canine


Validated    
Assay Code See Below
Description Mycobacterium is a genus of Actinobacteria, family Mycobacteriaceae. Over 190 species are recognized in this genus. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis (Mycobacterium tuberculosis) and leprosy (Mycobacterium leprae) in humans. Bovine tuberculosis is a chronic disease of animals and humans caused by Mycobacterium bovis. In a large number of countries it is a major infectious disease among cattle, other domesticated animals, and certain wildlife species. Other members of the Mycobacterium genus include M. caprae (considered to be a primary pathogen of goats) and M. pinnipedii, a pathogen of fur seals and sea lions. Aerosol exposure to M. bovis is considered to be the most frequent route of infection of cattle, but infection by ingestion of contaminated material also occurs. After infection, nonvascular nodular granulomas known as tubercles may develop. Characteristic tuberculous lesions occur most frequently in the lungs and the retropharyngeal, bronchial and mediastinal lymph nodes as well as liver, spleen and other organs. Clinical signs include weakness, anorexia, emaciation, dyspnoea, enlargement of lymph nodes, and cough, particularly with advanced tuberculosis.

Mycobacterium avium subspecies paratuberculosis (MAP) is an obligate pathogenic bacterium and the causative agent of Johne's disease, which affects ruminants such as cattle, and also causes Crohn's disease in humans.

Avian tuberculosis, or avian mycobacteriosis, is an important disease that affects companion, captive exotic, wild and domestic birds and mammals and is most often caused by Mycobacterium avium subsp. avium (M. a. avium).The disease is characterized by chronic and progressive wasting, weakness and diarrhoea. The primary lesions of avian tuberculosis in birds are nearly always in the intestinal tract. Diagnosis of avian tuberculosis in birds depends on the demonstration of M. avium avium) in excretions or secretions of live birds or liver and spleen of dead birds.

Pathogens Tested
  • APM-037 : Mycobacterium avium subspecies avium (This assay includes the detection of Mycobacterium species and Mycobacterium avium subspecies avium.)
  • APM-038 : Mycobacterium Species (This assay includes the detection of Mycobacterium species only. This Assay can detect M. austroafricanum, M.avium subsp. avium,M.bovis BCG, M.chelonae,M.gordonae, M.fortuitum subsp.fortuitum, M.insubricum, M.intracellulare, M.kansasii, M.marium, M.mucogenicum, M.peregrinum, M.porcinum, M.scrofulaceum, M.setense, M.simiae, M.smegmatis, M.terrae, M.tuberculosis, M.ulcerans, M.xenopi)
  • APM-039 : Mycobacterium avium subspecies paratuberculosis (This assay includes the detection of Mycobacterium species and Mycobacterium avium subspecies paratuberculosis.)
  • APM-100: Mycobacterium tuberculosis (This assay includes the detection of Mycobacterium species and Mycobacterium tuberculosis.)

Method Real- Time PCR.
Sample Type
Tissue (Intestinal tract, liver, spleen), Stool, Culture, Swab/Secretion (Respiratory), EDTA Blood, Milk, CSF, Gastric Lavage, Tissue on FTA Card.
Transport Condition Samples should be transported at 4°C. Stool and milk must be frozen after collection.
Turn Around Time (TAT) Normal Turnaround time for pathogen Identification is within 5 working days.
Urgent Samples will be reported within half of the minimum test period & will be Charged Double.
Samples delivered after 11:00 AM will be processed next working day unless urgent.

Links