Molecular Biology & Genetics Laboratory

Pathogen Identification


Molecular based methods have advanced the laboratory testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens. We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG Lab is ISO 15189 accredited and benefits from a stand-alone containment Level 3 facility where samples for highly contagious pathogen are received and processed.


All Bacteria Virus Fungi Parasite

Validated
Assay Code HPT-049
Description Human African trypanosomiasis, also known as sleeping sickness, is a vector-borne parasitic disease. It is caused by infection with protozoan parasites belonging to the genus Trypanosoma. They are transmitted to humans by tsetse fly (Glossina genus) bites which have acquired their infection from human beings or from animals harbouring human pathogenic parasites. Human African trypanosomiasis takes 2 forms, depending on the parasite involved.

This assay is used for the detection of both T. evansi and T.brucei, however, it can not be used to differentiate between the two subtypes.

Pathogens Tested
  • Trypanosoma brucei gambiense is found in 24 countries in west and central Africa. This form currently accounts for over 98% of reported cases of sleeping sickness and causes a chronic infection. A person can be infected for months or even years without major signs or symptoms of the disease. When more evident symptoms emerge, the patient is often already in an advanced disease stage where the central nervous system is affected.
  • Trypanosoma brucei rhodesiense is found in 13 countries in eastern and southern Africa. Nowadays, this form represents under 2% of reported cases and causes an acute infection. First signs and symptoms are observed a few months or weeks after infection. The disease develops rapidly and invades the central nervous system. Only Uganda presents both forms of the disease, but in separate zones.

Method Real-Time PCR.
Sample Type
EDTA blood, Culture.
Transport Condition Samples should be transported at 4°C.
Turn Around Time (TAT) TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.

Links




Molecular Biology & Genetics Laboratory

Pathogen Identification


Molecular based methods have advanced the laboratory testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens. We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG Lab is ISO 15189 accredited and benefits from a stand-alone containment Level 3 facility where samples for highly contagious pathogen are received and processed.


All Bacteria Virus Fungi Parasite

Validated
Assay Code HPT-049
Description Human African trypanosomiasis, also known as sleeping sickness, is a vector-borne parasitic disease. It is caused by infection with protozoan parasites belonging to the genus Trypanosoma. They are transmitted to humans by tsetse fly (Glossina genus) bites which have acquired their infection from human beings or from animals harbouring human pathogenic parasites. Human African trypanosomiasis takes 2 forms, depending on the parasite involved.

This assay is used for the detection of both T. evansi and T.brucei, however, it can not be used to differentiate between the two subtypes.

Pathogens Tested
  • Trypanosoma brucei gambiense is found in 24 countries in west and central Africa. This form currently accounts for over 98% of reported cases of sleeping sickness and causes a chronic infection. A person can be infected for months or even years without major signs or symptoms of the disease. When more evident symptoms emerge, the patient is often already in an advanced disease stage where the central nervous system is affected.
  • Trypanosoma brucei rhodesiense is found in 13 countries in eastern and southern Africa. Nowadays, this form represents under 2% of reported cases and causes an acute infection. First signs and symptoms are observed a few months or weeks after infection. The disease develops rapidly and invades the central nervous system. Only Uganda presents both forms of the disease, but in separate zones.

Method Real-Time PCR.
Sample Type
EDTA blood, Culture.
Transport Condition Samples should be transported at 4°C.
Turn Around Time (TAT) TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.

Links