Molecular Biology & Genetics Laboratory

Pathogen Identification


Molecular based methods have advanced the laboratory testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens. We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG Lab is ISO 15189 accredited and benefits from a stand-alone containment Level 3 facility where samples for highly contagious pathogen are received and processed.


All Bacteria Virus Fungi Parasite


Validated
Assay Code HPR-192
Description Rabies is a zoonotic disease that can affect all mammals. It is caused by Rabies lyssavirus, which is a neurotropic virus and is the type species of the Lyssavirus genus of the Rhabdoviridae family. These viruses are enveloped and have a single stranded negative-sense RNA genome. Rabies virus is primarily transmitted through the saliva of an infected animal. Saliva becomes infectious a few days prior to the onset of clinical signs. Infection occurs primarily via bite wounds, or infected saliva entering an open cut or wound or mucous membranes, such as those in the mouth, nasal cavity, or eyes. Occasional, albeit rare, transmission by inhalation of infected aerosol has been described.

The incubation period varies from a few days to 6 months. Clinical observations may only lead to a suspicion of rabies because signs of the disease are not pathognomonic and may vary greatly from one animal to another. The only way to undertake a reliable diagnosis is to identify the virus or viral antigen / viral RNA using laboratory tests.The disease has important social costs due to human mortality and high economic consequences due to the losses in livestock and the cost of the implementation of preventive and control measures in both animals and humans.

Method Real-Time RT-PCR
Sample Type
Swab / Secretion (Respiratory), Tissue (Brain), Culture.
Transport Condition Samples should be transported at 4°C and delivered within 24h of collection.
Specimens must be sent in RNA Preservative media. Please contact MBG Lab in advance for correct package and transport requirements.
Turn Around Time (TAT) TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.

Links




Molecular Biology & Genetics Laboratory

Pathogen Identification


Molecular based methods have advanced the laboratory testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens. We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG Lab is ISO 15189 accredited and benefits from a stand-alone containment Level 3 facility where samples for highly contagious pathogen are received and processed.


All Bacteria Virus Fungi Parasite


Validated
Assay Code HPR-192
Description Rabies is a zoonotic disease that can affect all mammals. It is caused by Rabies lyssavirus, which is a neurotropic virus and is the type species of the Lyssavirus genus of the Rhabdoviridae family. These viruses are enveloped and have a single stranded negative-sense RNA genome. Rabies virus is primarily transmitted through the saliva of an infected animal. Saliva becomes infectious a few days prior to the onset of clinical signs. Infection occurs primarily via bite wounds, or infected saliva entering an open cut or wound or mucous membranes, such as those in the mouth, nasal cavity, or eyes. Occasional, albeit rare, transmission by inhalation of infected aerosol has been described.

The incubation period varies from a few days to 6 months. Clinical observations may only lead to a suspicion of rabies because signs of the disease are not pathognomonic and may vary greatly from one animal to another. The only way to undertake a reliable diagnosis is to identify the virus or viral antigen / viral RNA using laboratory tests.The disease has important social costs due to human mortality and high economic consequences due to the losses in livestock and the cost of the implementation of preventive and control measures in both animals and humans.

Method Real-Time RT-PCR
Sample Type
Swab / Secretion (Respiratory), Tissue (Brain), Culture.
Transport Condition Samples should be transported at 4°C and delivered within 24h of collection.
Specimens must be sent in RNA Preservative media. Please contact MBG Lab in advance for correct package and transport requirements.
Turn Around Time (TAT) TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.

Links