Molecular Biology & Genetics Laboratory

Pathogen Identification


Molecular based methods have advanced the laboratory testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens. We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG Lab is ISO 15189 accredited and benefits from a stand-alone containment Level 3 facility where samples for highly contagious pathogen are received and processed.


All Bacteria Virus Fungi Parasite


Validated
Assay Code HPG-073
Description STD Panel is an in vitro test for the detection of viral and bacterial DNA as an aid in the Evaluation of infections by Chlamydia trachomatis, Neisseria gonorrheae, Mycoplasma genitalium, Herpes simplex virus 1 & 2, Treponema pallidum. These infections are sexually transmitted and can be life threatening if left untreated.

To prevent getting a sexually transmitted disease, or STD, always avoid sex with anyone who has genital sores, a rash, discharge, or other symptoms. Use of barrier devices during intercourse can prevent the spread of STD.

Pathogens TestedChlamydia trachomatis is an obligate intracellular bacteria commonly causing sexually transmitted disease that can lead to infertility. Usually asymptomatic in women, some develop pelvic inflammatory disease, unusual vaginal bleeding or discharge. In males symptoms such as infectious urethritis, painful or burning sensation when urinating, an unusual discharge from the penis, swollen or tender testicles, or fever are seen. Occasionally infection may spread to the epididymis (storage tubes for sperm overlying the testes in the testicle), which can be very painful and may lead to infertility. Chlamydia can also be passed from an infected mother to her baby during vaginal childbirth.

Neisseria gonorrhoeae - Neisseria gonorrhoeae, also known as gonococci, is a species of Gram-negative bacteria responsible for the sexually transmitted infection gonorrhea in both men and women. Often, gonorrhea has no symptoms. Most people are not aware that they have the infection - especially women. Some women may have symptoms such as vaginal discharge, lower abdominal pain or pain with intercourse. If left untreated it can lead to long term complication such as pelvic inflammatory disease, ectopic pregnancy and infertility. Most men who are infected have symptoms such as urethritis associated with burning with urination and discharge from the penis. In both men and women if gonorrhea is left untreated, it may spread locally causing epididymitis throughout the body, affecting joints and heart valves. Gonorrhea can also be passed from a woman to her fetus during birth.

Mycoplasma genitalium - Mycoplasma genitalium is a small parasitic bacterium which lives on cilated epithelial cells of the genital tract and is sexually transmitted. In women, symptoms such as vaginal itching, burning while urinating, discharge, pain during intercourse may appear. In the long term, this infection is suspected to cause pelvic inflammatory disease and cervicitis. In men it is a major agent in urogenital tract disease.

Herpes simplex virus 1 & 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family, Herpesviridae, that cause genital ulcers. HSV is a sexually transmitted disease. HSV-1 is associated with many clinical manifestations including gingivostomatitis, eye infections, and various skin complications including cold sores, whitlow and super infection of eczema. HSV-2 is sexually transmitted and produces painful sores, usually in the genital area.HSV can also cause meningitis or encephalitis. Sometimes genital herpes infection can lead to miscarriage or premature birth. Herpes infection can be passed from mother to child resulting in a potentially fatal infection (neonatal herpes).

Treponema pallidum is a spirochaete bacterium with subspecies that cause treponemal diseases such as syphilis, bejel, pinta which spread through close sexual contact. Syphilis is a highly contagious disease spread primarily by sexual activity. The bacteria pass through intact mucous membranes and abraded skin; they are then carried by the blood stream to every organ in the body. The symptoms of syphilis depend on the stage of the disease. Many people do not have symptoms. In general, painless sores and swollen lymph nodes are possible symptoms of primary syphilis. Those with secondary syphilis may also have fever, fatigue, rash, aches and pains, and loss of appetite, among other symptoms. Tertiary syphilis causes heart, brain, and nervous system problems. The organism can also be transmitted to a fetus by transplacental passage during the later stages of pregnancy, giving rise to congenital syphilis.

Method Real-Time PCR
Sample Type
Swab / Secretion (Genital) , Swab / Secretion (Rectal), Swab / Secretion (Abscess), Urine.
Transport Condition Samples should be transported at 4°C.
Turn Around Time (TAT) TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.

Please, contact MBG Lab for more information




Molecular Biology & Genetics Laboratory

Pathogen Identification


Molecular based methods have advanced the laboratory testing to faster and better diagnostics. PCR methods, microarray and next generation sequencing have provided speed and high level of accuracy. Molecular biology based methods are sensitive and quick to detect microbial pathogens in various clinical specimens. We offer molecular detection of pathogenic viruses, bacteria and parasites from clinical specimens. MBG Lab is ISO 15189 accredited and benefits from a stand-alone containment Level 3 facility where samples for highly contagious pathogen are received and processed.


All Bacteria Virus Fungi Parasite


Validated
Assay Code HPG-073
Description STD Panel is an in vitro test for the detection of viral and bacterial DNA as an aid in the Evaluation of infections by Chlamydia trachomatis, Neisseria gonorrheae, Mycoplasma genitalium, Herpes simplex virus 1 & 2, Treponema pallidum. These infections are sexually transmitted and can be life threatening if left untreated.

To prevent getting a sexually transmitted disease, or STD, always avoid sex with anyone who has genital sores, a rash, discharge, or other symptoms. Use of barrier devices during intercourse can prevent the spread of STD.

Pathogens TestedChlamydia trachomatis is an obligate intracellular bacteria commonly causing sexually transmitted disease that can lead to infertility. Usually asymptomatic in women, some develop pelvic inflammatory disease, unusual vaginal bleeding or discharge. In males symptoms such as infectious urethritis, painful or burning sensation when urinating, an unusual discharge from the penis, swollen or tender testicles, or fever are seen. Occasionally infection may spread to the epididymis (storage tubes for sperm overlying the testes in the testicle), which can be very painful and may lead to infertility. Chlamydia can also be passed from an infected mother to her baby during vaginal childbirth.

Neisseria gonorrhoeae - Neisseria gonorrhoeae, also known as gonococci, is a species of Gram-negative bacteria responsible for the sexually transmitted infection gonorrhea in both men and women. Often, gonorrhea has no symptoms. Most people are not aware that they have the infection - especially women. Some women may have symptoms such as vaginal discharge, lower abdominal pain or pain with intercourse. If left untreated it can lead to long term complication such as pelvic inflammatory disease, ectopic pregnancy and infertility. Most men who are infected have symptoms such as urethritis associated with burning with urination and discharge from the penis. In both men and women if gonorrhea is left untreated, it may spread locally causing epididymitis throughout the body, affecting joints and heart valves. Gonorrhea can also be passed from a woman to her fetus during birth.

Mycoplasma genitalium - Mycoplasma genitalium is a small parasitic bacterium which lives on cilated epithelial cells of the genital tract and is sexually transmitted. In women, symptoms such as vaginal itching, burning while urinating, discharge, pain during intercourse may appear. In the long term, this infection is suspected to cause pelvic inflammatory disease and cervicitis. In men it is a major agent in urogenital tract disease.

Herpes simplex virus 1 & 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family, Herpesviridae, that cause genital ulcers. HSV is a sexually transmitted disease. HSV-1 is associated with many clinical manifestations including gingivostomatitis, eye infections, and various skin complications including cold sores, whitlow and super infection of eczema. HSV-2 is sexually transmitted and produces painful sores, usually in the genital area.HSV can also cause meningitis or encephalitis. Sometimes genital herpes infection can lead to miscarriage or premature birth. Herpes infection can be passed from mother to child resulting in a potentially fatal infection (neonatal herpes).

Treponema pallidum is a spirochaete bacterium with subspecies that cause treponemal diseases such as syphilis, bejel, pinta which spread through close sexual contact. Syphilis is a highly contagious disease spread primarily by sexual activity. The bacteria pass through intact mucous membranes and abraded skin; they are then carried by the blood stream to every organ in the body. The symptoms of syphilis depend on the stage of the disease. Many people do not have symptoms. In general, painless sores and swollen lymph nodes are possible symptoms of primary syphilis. Those with secondary syphilis may also have fever, fatigue, rash, aches and pains, and loss of appetite, among other symptoms. Tertiary syphilis causes heart, brain, and nervous system problems. The organism can also be transmitted to a fetus by transplacental passage during the later stages of pregnancy, giving rise to congenital syphilis.

Method Real-Time PCR
Sample Type
Swab / Secretion (Genital) , Swab / Secretion (Rectal), Swab / Secretion (Abscess), Urine.
Transport Condition Samples should be transported at 4°C.
Turn Around Time (TAT) TAT for routine samples is within 3 working days. Urgent Samples will be charged double and will be reported within 1-2 working days.
Samples delivered before 11:00 AM will begin processing immediately resulting in shorter TAT.

Please, contact MBG Lab for more information